I have a Toshiba P25-S5201 running Debian GNU/Linux (unstable branch)
with great success.

I am including my XF86Config-4 file with the sections for external
monitor and TV commented out. You must install the commercial NVidia
drivers (driver: nvidia) for this configuration file to work.

I got the modem working through the i810 modem driver in the 2.6 kernel.
It is part of the ALSA sound system drivers. You will still have to run
the smartlink daemon with the "--alsa" parameter for it to create and
manage the /dev/ttySL0 modem device. After that, it works like a champ!

I have given up on suspend/hibernation mode. I can't get ACPI to work
completely.

I am now trying to get the extra keys to the right of the keyboard to
work.